MedBalans

Cholecystitis / cholangitis

Adults · verify locally

Inpatient

First line

  • Piperacillin/tazobactam · i.v.

    4.5 g IV q6–8h

Alternatives

  • Ceftriaxone + metronidazole · i.v.

    Ceftriaxone 1–2 g daily + metro 500 mg IV tid

  • Ciprofloxacin + metronidazole · i.v.

    Cipro 400 mg IV bid + metro 500 mg IV tid

Duration

Until source control + short post-drainage course (often 4–7 days)

  • • Tokyo Guidelines TG18 (2018)