COPD exacerbation (when antibiotics indicated)
Adults · verify locally
Inpatient / outpatient
First line
- Amoxicillin/clavulanate · p.o.
875/125 mg PO bid
Alternatives
- Doxycycline · p.o.
100 mg PO bid
- Azithromycin · p.o.
500 mg day 1, then 250 mg daily ×4
Duration
5 days
- • GOLD COPD (2025)