Algorithm
- Confirm cardiac arrest (unresponsive, not breathing normally) → call help / arrest team; start high-quality CPR immediately (rate 100–120/min, depth 5–6 cm, full recoil, minimize interruptions).
- Attach defibrillator/AED early; continue CPR while pads applied. Prefer antero-lateral pads; place lateral pad in mid-axillary line below the armpit (ERC 2025).
- Shockable rhythm (VF/pVT): defibrillate ASAP (≥150 J biphasic first shock or manufacturer dose); resume CPR immediately for 2 min; minimize peri-shock pause (<5 s).
- Adrenaline 1 mg IV: as soon as possible for non-shockable rhythms; AFTER the 3rd shock for shockable rhythms; then every 3–5 min while ALS continues (ERC 2025).
- Amiodarone 300 mg IV after a total of 3 shocks for VF/pVT; further 150 mg after a total of 5 shocks. Lidocaine 100 mg (+50 mg after 5 shocks) if amiodarone unavailable.
- Airway: stepwise to effective ventilation; highest feasible FiO₂ during CPR; tracheal intubation only by skilled operators with waveform capnography; ventilate ~10/min once advanced airway in place without interrupting compressions.
- Vascular access: attempt IV first (≤2 attempts); then IO if needed. Treat reversible causes (4H/4T) without delay. Do not routinely give calcium, bicarbonate, or steroids.
- After ROSC: ABC, SpO₂ 94–98% (avoid hyperoxia), 12-lead ECG, treat cause (ACS pathway), targeted temperature / neuroprognostication per local post-resuscitation protocol; consider ECPR in selected refractory arrests where available.
Red flags
- • Long interruptions in chest compressions
- • Adrenaline given too early in shockable rhythm (before 3rd shock) contrary to ERC 2025
- • Missed reversible causes (4H/4T)
- • Hyperoxia after ROSC
Medications by step
Shockable VF/pVT
- Defibrillation · —
≥150 J biphasic first (or device dose); CPR 2 min between shocks
- Adrenaline · i.v. / i.o.
1 mg IV/IO after 3rd shock, then q3–5 min
- Amiodarone · i.v.
300 mg IV after 3 shocks; 150 mg after 5 shocks
Non-shockable PEA/asystole
- Adrenaline · i.v. / i.o.
1 mg IV/IO ASAP, then q3–5 min
Alternatives / special
- Lidocaine · i.v.
100 mg IV after 3 shocks if no amiodarone; +50 mg after 5 shocks
- Thrombolysis · i.v.
Consider if PE is suspected/confirmed cause of arrest; prolonged CPR 60–90 min may be needed
References
Updated: Июль 2026
