Algorithm
- Check responsiveness and pulse; start CPR if pulseless; attach defibrillator/monitor early.
- Identify rhythm class: shockable (VF/pVT) vs non-shockable (PEA/asystole) vs bradycardia vs tachycardia with pulse.
- Follow the matching form protocol below — do not mix algorithms.
- Give oxygen, obtain IV/IO access, treat reversible causes (4H and 4T).
- After ROSC or rate control: 12-lead ECG, bloods, seek expert help / CCU-ICU.
Red flags
- • No pulse — arrest algorithm first, not oral antiarrhythmics
- • Unstable tachycardia with pulse — cardioversion, not prolonged drug trials
- • Mobitz II / complete AV block — prepare pacing
- • Consider toxins / hyperkalemia / ACS
Medications by step
Overview — key adult doses
- Adrenaline · i.v. / i.o.
Arrest: 1 mg IV/IO q3–5 min; bradycardia infusion 2–10 mcg/min
- Amiodarone · i.v.
Arrest VF/pVT: 300 mg then 150 mg; stable VT: 300 mg over 10–60 min
- Atropine · i.v.
Bradycardia: 500 mcg IV; repeat to max 3 mg
Help by rhythm form
Separate short protocols for each emergency rhythm — follow the form you see on the monitor.
VF / pulseless VT
- Confirm cardiac arrest → high-quality CPR; minimize interruptions; attach defibrillator.
- Shock as soon as ready: ≥150 J biphasic (or manufacturer dose); immediately resume CPR 2 min; peri-shock pause <5 s.
- After a total of 3 shocks: adrenaline 1 mg IV/IO; then every 3–5 min (ERC 2025 — not after the 2nd shock).
- After a total of 3 shocks: amiodarone 300 mg IV/IO; after a total of 5 shocks: amiodarone 150 mg (refractory or recurrent VF/pVT).
- If amiodarone unavailable: lidocaine 100 mg IV, then 50 mg after 5 shocks.
- Refractory VF after 3 shocks: confirm mid-axillary pad position; consider antero-posterior pad vector change (ERC 2025). Dual sequential defibrillation is not routinely recommended.
- Between cycles: airway/oxygenation, prefer IV access first, treat 4H/4T.
Red flags
- • Refractory VF after ≥3 shocks — seek 4H/4T, hyperK, ACS, toxins
- • Long CPR pauses for intubation
Medications by step
Defibrillation
- Defibrillation · —
150–200 J biphasic; CPR 2 min between shocks
Arrest drugs
- Adrenaline · i.v. / i.o.
1 mg IV/IO after 3rd shock, then q3–5 min
- Amiodarone · i.v. / i.o.
300 mg IV/IO after 3 shocks; 150 mg after 5 shocks
- Lidocaine · i.v.
100 mg IV if no amiodarone; +50 mg after 5 shocks
PEA / asystole
- Non-shockable rhythm: do NOT defibrillate. Continuous high-quality CPR.
- Adrenaline 1 mg IV/IO as soon as possible, then every 3–5 min.
- Confirm asystole in ≥2 leads; check leads/pads; treat PEA as organized ECG without pulse.
- Aggressively reverse 4H/4T (hypoxia, hypovolemia, hypo/hyperkalemia, hypothermia; thrombosis, tamponade, toxins, tension pneumothorax).
- Reassess rhythm every 2 min; if VF/pVT appears → switch to shockable algorithm.
Red flags
- • False asystole from disconnected leads
- • Missing reversible causes (hypovolemia, tension PTX, PE, hyperK)
Medications by step
PEA / asystole drugs
- Adrenaline · i.v. / i.o.
1 mg IV/IO ASAP, then q3–5 min
Symptomatic bradycardia
- Assess ABCs, oxygen if hypoxic, IV access, 12-lead ECG when stable enough.
- Unstable signs: shock, syncope, acute heart failure, ischemic chest pain, altered mentation → treat immediately.
- Atropine 500 mcg IV; repeat every 3–5 min to max 3 mg.
- If atropine fails or high-degree block: prepare transcutaneous pacing; sedation/analgesia if conscious.
- Second-line infusions: adrenaline 2–10 mcg/min IV or isoprenaline/dopamine per local protocol while arranging TCP/TVP.
- Seek expert help early for AV block, acute MI, or toxin-related bradycardia.
Red flags
- • Mobitz II / complete AV block — do not rely on atropine alone
- • ACS as the cause
Medications by step
Bradycardia therapy
- Atropine · i.v.
500 mcg IV q3–5 min; max 3 mg
- Adrenaline infusion · i.v. infusion
2–10 mcg/min IV if atropine/pacing insufficient
- Transcutaneous pacing · —
Capture then set rate ~60–70/min; check pulse
Unstable tachycardia (with pulse)
- Confirm pulse present but patient unstable (shock, ischemia, acute HF, severe hypotension, altered mentation).
- Synchronized cardioversion: sedation if conscious; energy per local protocol (often start ~70–120 J biphasic for narrow regular; higher for irregular/wide).
- If VT with pulse and unstable → synchronized cardioversion (not defibrillation unless pulseless).
- If delays to cardioversion and regular narrow-complex: adenosine 6 mg rapid IV push may be diagnostic/therapeutic while preparing shock.
- After conversion: 12-lead ECG, treat cause (ischemia, electrolytes, drugs), monitor for recurrence.
Red flags
- • Pulse lost while preparing → switch to arrest algorithm
- • Unsynchronized shock with a pulse risks inducing VF
Medications by step
Unstable tachycardia
- Synchronized cardioversion · —
Per device/protocol; escalate energy if fails
- Adenosine · i.v.
6 mg rapid IV flush (optional while preparing shock if regular narrow)
Stable narrow-complex tachycardia / AF with RVR
- Confirm stability (adequate BP/perfusion, no severe ischemia/acute HF).
- Regular narrow (likely AVNRT/AVRT): vagal maneuvers → adenosine 6 mg rapid IV, then 12 mg if needed (max per protocol).
- Irregular narrow (AF/flutter with RVR): rate control if duration unknown or >48 h without anticoagulation plan — beta-blocker or nondihydropyridine CCB IV per local protocol; digoxin if HF/hypotension risk with those agents.
- Avoid routine immediate cardioversion for stable AF of unknown duration without anticoagulation / TEE strategy.
- Wide-complex stable tachycardia: treat as VT until proven otherwise — expert help; amiodarone 300 mg IV over 10–60 min often used; avoid AV-nodal blockers if accessory pathway suspected (pre-excited AF).
Red flags
- • Pre-excited AF (WPW) — do not use verapamil/digoxin/adenosine for rate control
- • Becomes unstable → cardioversion
Medications by step
Stable SVT / AF RVR
- Adenosine · i.v.
6 mg rapid IV; then 12 mg if needed (regular narrow)
- Metoprolol / esmolol or verapamil / diltiazem · i.v.
IV rate control for AF RVR per local protocol if stable
- Amiodarone · i.v.
300 mg IV over 10–60 min for stable wide-complex VT suspected
References
- • ERC Guidelines 2025 — Adult ALS (2025)
- • AHA — ACLS algorithms (2020)
Updated: Июль 2026
