Clinical context (Late neonate/infant 2–8 weeks with progressive non-bilious projectile vomiting, hungry after vomit, palpable pyloric olive, hypochloremic hypokalemic metabolic alkalosis — surgical (pyloromyotomy) after medical stabilization)
First-line therapy
IV fluid and electrolyte correction BEFORE surgical referral • —
Duration: Until transfer / definitive care · ABCDE; NPO; correct dehydration and hypochloremic alkalosis with isotonic IV fluids (0.9% NaCl ± KCl per labs); monitor urine output and electrolytes; urgent pediatric surgery consult for pyloromyotomy — NOT simple GER
Supportive care only — no routine antibiotics • —
Duration: Until postoperative feeds · Antibiotics not indicated for uncomplicated HPS — add only if concurrent infection suspected (APSA, AAP)